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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

5. 2012年搞笑诺贝尔奖之化学奖
We asked the Dachis Group, a social media measurement agency, to tell us which brands got the biggest increases in consumer love, and which lost the most ground.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Also important to EMBA entrepreneurs was the support of their school and alumni network. About three-quarters of entrepreneurs thought that both the school and their alumni network were helpful or very helpful when setting up their company. “Alumni support was key to getting the idea vetted and getting the right contacts needed for the business”, said one.
No, this doesn't mean you should abandon your LinkedIn profile for fear of a suspicious boss. But it does mean you should be more careful. For one, turn off your activity broadcasts so that every savvy move you make isn't announced to your entire network. Here's how: From the homepage, hover over your photo in the top right corner, and click on "Privacy & Settings." From this page, click "Turn on/off your activity broadcasts."

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 北京今年新增减税规模预计400亿
Open Access Perspective

Soft matter science and the COVID-19 pandemic

n. 释放,让渡,发行

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

For many Western whites, opportunities for achieved identity — the top of the hill — seem unattainable. So their ascribed identity — their whiteness — feels more important than ever.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Popular songs from 2012:”Di Da” (Kan Kan and Li Chen) and “You Exist In My Song”(Qu Wanting and Du Chun)
The other two manufacturers, OPPO and vivo, both achieved growth of over 100 percent, shipping 99.4 million and 77.3 million units respectively in 2016.
因此,39%的90后试图避免使用手机所带来的负面影响,措施包括关闭APP的消息提示功能、限制社交媒体互动频率、以及在某些情况下完全不使用社交媒体等等。
France, one of the most visited countries in the world, ranks No. 9 overall. It is No. 2 in Cultural Influence and No. 6 in Power.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Executives from PwC immediately realized there was a problem, but they were too late to rectify the mistake as Dunaway read out the name La La Land from a card that was meant to be for the Best Actress award, which Emma Stone won for her role in the film earlier in the night.
It is based on a survey of business schools and another of their alumni who graduated in 2013.
中国股市的跌势仍在继续,现在“红线”已触,一切都提早结束了。
随着《喜羊羊与灰太狼》大电影第二部《喜羊羊与灰太狼之虎虎生威》的上映,这部空前火爆的国产动画再度成为众人关注的焦点。你知道怎么用英文介绍《喜羊羊与灰太狼》么?I

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 专家聚焦完善住房保障体系
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

8.触感人造手

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

《极盗车神》

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Faber laughs at Bernanke's remark that the economy would be strong enough later this year so he could take his foot off the gas, that is begin 'tapering, or scaling back it's stimulative quantitative easing (QE) program later this year.' Yes, laughed.
Many successful entrepreneurs started later in life. J. K. Rowling (Harry Potter author), Julia Child (chef), and Sam Walton (Wal-Mart) all started their wildly successful brands after they were comfortably along in their lives. Having the experience that comes with age can give you a unique outlook on your business. Life experiences bring depth that the most educated young adult, by his or her nature, is less able to foresee.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

今年到目前为止,周星驰的《美人鱼》自二月上旬的贺岁档上映以来,已经取得了5.26亿美元的票房收入。
在西方国家更新、更广泛的国民身份认同里,白人们也有自己的一席之地。但是除非他们接受这一点,“白”的危机仍会持续存在下去。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

据国家统计局上周三发布的调查显示,去年,我国人口总数有所增长,且男女性别比例及国民受教育程度均有所改善。
同期,巴西和俄罗斯分别减持到2617亿美元和1089亿美元。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 预测:2018楼市 房价“最稳”的一年
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

NASA and the other American agency that maintains long-term temperature records, the National Oceanic and Atmospheric Administration, issued separate data compilations on Friday that confirmed the 2014 record. A Japanese agency had released preliminary information in early January showing 2014 as the warmest year.
这项测试的答案没有对错,只要对自己诚实即可。
Texas was one of the first states to emerge from the recession and it continues to attract companies on the basis of its low tax burden, predictable regulatory environment and skilled labor force. Texas employment is expected to expand 3% annually through 2017, according to Moody’s. (Arizona’s forecasted rate is a microscopic 0.04% better). Texas has attracted a lot of attention from California companies and Governor Rick Perry has not been shy about contrasting the business climates of the two states. California firms EBay and Electronic Arts have both chosen Texas for large expansions in recent years. Austin has been a hotbed of activity this year with Accenture
In 2011, at age 15, D'Aloisio closed a seed round of funding from Li Ka-shing. A year later, Summly launched, and within a month it had attracted 500,000 users and became the number-one news app in 28 countries. The Yahoo! sale capped off a remarkable run for someone not yet out of high school. But it's not mere technological savvy that sets D'Aloisio apart. Since long before he could shave, he has been driven by an intense curiosity and a desire to make some sort of mark on the tech world. Not just to create but to build and, yes, to monetize.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Trium跃升3名,击败由凯洛格管理学院(Kellogg School of Management)与香港科技大学(HKUST)联合推出的课程,后者多年来一直高居排行榜榜首。这是Trium首次登上排行榜榜首,也是14年来第四个登上榜首的课程。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

adj. 复杂的,复合的,合成的
China’s outbound non-financial investment fell 40.9 per cent during the ten months through October, according to official figures, reflecting the enduring impact of strict capital controls.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 四季度建材家居市场信心仍显不足
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

根据周一上海电视台的报道,2015年,上海市外来常住人口出现15年来的首次负增长。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Big Little Lies

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

It was the fastest growth rate among the top 10 countries on the EPO's patent-filing league table.
The upshot: The world's largest economy can still function as an oasis in a desert despite the claims of doomsayers that those days are over.
求职市场很艰难并非意味着找到工作是不可能。Challenger说:“你应该更努力地去找工作。”
据BusinessInsider.com报道,麦嘉华夸张地说,“QE基本上会成为我们下半辈子日常生活的一部分”。麦嘉华还说,2010年在贝南克灾难性试验的早期阶段,他曾给出“美联储奔向QE99”的警告。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

No. Football punditry is a mug’s game. Better to have the benefit of hindsight. There have been 20 previous World Cups. Of those, Brazil (five titles) and Germany (four), are regular contenders. Home advantage helps, with host nations winning the trophy six times. But next year’s festival of football is being held in Russia, which has the lowest-ranked team in the tournament.
comfort
2.Hold themselves and others accountable
NPLs rose from 1.25 per cent of total loans to 1.67 per cent by the end of 2015, amounting to Rmb1.27tn held by commercial banks.
Hua Xu Yin

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

尽管2016年受调查机场的平均准点率同比提高7%至70.4%,但航班平均延误时长为33分钟。
Producing fake data, it appears, is condoned at official levels. Publishing real data lands you up in court. Much more of this and the public will be right to lose trust in official statistics.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

库克公开性取向的举动,提供了一个罕有的机会,让人们得以一窥他保护严密的个人生活,但同时也让苹果品牌在一些不太宽容的地方面临风险。库克在阿拉巴马州长大的经历促使他作出此举,他曾说在阿拉巴马州看到的一些歧视现象“简直让我感到恶心”。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

谈到乌克兰,普京再次否认俄罗斯军队在东乌克兰境内活动。那里的亲俄罗斯分离主义运动正在与乌克兰政府军作战。但是他说,莫斯科从未否认有人在那里开展属于“军事领域”的行动。他还说,俄罗斯没有制裁乌克兰的计划,但不会让乌克兰享受优惠贸易待遇。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

"To make the world a better place, I invented a transformative water purifier," Google quoted Zhang as saying. "It takes in dirty and polluted water from rivers, lakes and even oceans, then massively transforms the water into clean, safe and sanitary water. When humans and animals drink this water, they will live a healthier life."
我是否工作太辛苦了?花时间重新调整一下,花时间做令你愉快的事情是非常重要的。必要时释放你的欲望,从工作或学习压力中解脱出来,给自己时间去自由呼吸,即便一次只有几分的时间。
n. 怪
总的来说,在选择就读EMBA的原因中,创业排在最末(10分中得5.5分)。学员的主要动机是学习管理(9.1分)、拓宽人脉(8.3分)及增加收入(8.1分)。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

manifesto
China denies any wrongdoing and says it is working to tackle problems of industrial overcapacity that have become more acute as its economy has slowed.
需要注意的是,票房总收入和个人收入是两个不同的概念。在2012年6月到2013年6月期间(这是我们编制最新全球100名人榜所采用的时间段),唐尼的估计个人收入为7,500万美元,比强森多挣2,900万美元。而本文所讨论的数字是每位明星出演的电影在今年斩获的全球票房。
We will make our skies blue again.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

authority
4. 学会自我推销。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Chandelier is the 17th most viewed music video on TouTube of all time and has racked up more than 712 million hits.
['flimzi]
考夫曼和同事加雷思?哈里斯(Gareth Harris)发现,居住在那些人种快速多样化地域的英国白人更倾向于投给右翼的英国国家党(British National Party)。宾夕法尼亚大学政治学教授丹尼尔?霍普金斯(Daniel Hopkins)在美国发现了相似的民族变化导致反移民政策的规律。
Four government agencies including the commerce ministry and the central bank said in December they would apply tighter scrutiny to "irrational" outbound deals including real estate, hotels, movie theatres, entertainment assets and sports clubs.
沃伦·巴菲特自2014年以来再次排名第二,净资产由去年的608亿美元增加到756亿美元。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

n. 繁荣,兴旺
“A worker sent a text to a colleague saying he was quitting and asked her to forward it to management.”
Around 10 gigabytes of photos have allegedly been released. Jiedaibao, a popular online peer-to-peer lending platform, is involved in the incident, the Beijing Times reported on Dec. 1.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 软体家具新国标年内出台
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

5. Fred Hersch Trio “Floating” (Palmetto) The articulate grace of Fred Hersch’s current piano trio, with the bassist John Hébert and the drummer Eric McPherson, finds potent expression on an album structured like a nightclub set, with a few retooled standards mixed in with sturdy, emotionally transparent original songs.
[h?b]

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 陶瓷产业发展带出人才聚集效应
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 广东保障城市停车场建设用地
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 全国房产调控政策超400次
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

乔治王子获得满分,因为他对加拿大总理特鲁多傲慢的击掌回了一记冷眼。
创新对于推动竞争激烈的全球化世界的增长至关重要,2016年全球创新指数根据82个创新指标的表现对超过100个国家进行排名。中国从去年的第29名攀升至第25名,这也是第一次有中等收入国家进入前25强。
Phil Baty, editor of THE rankings, said: "China has introduced powerful policy drives, backed with serious funding, to produce world-class universities. In 2015, the country announced its excellence initiative, which aims to establish six of its universities in the leading group of global institutions by 2020."

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 迎接2.0时代绿建行业整装待发
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

学习管理和领导力技巧只是EMBA的一方面。一位毕业生表示:“它实际上让我成了一名创业家。”自四、五年前读EMBA以来,近三分之一(31%)的学员创办了自己的公司,或者打算创办公司。英国《金融时报》的数据显示,这些企业中91%如今仍在运营。
俄罗斯为世界上第十大经济体,除了天然气(碳氢化合物),经济贡献甚微。腐败和寻租行为使经济蒙受巨大损失。它依然沿用着苏联时代的基础设施,并且满足国民教育、医疗需求的能力正急速下滑。
Hurun’s China Rich List, which tracks more than 2,000 private entrepreneurs with a net worth of $300m or higher, added 179 names to its roster this year.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: “内忧外患”逼中国陶瓷行业升级
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

这张专辑中十分突出的一首歌《Him》(《他》)以低调的方式讲述了一个有关同性恋和文化偏执的催人泪下的故事,是一首倡导非异性恋者公民权的歌曲。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Feng said that the Goal for 2017 is to maintain an overall punctuality rate of about 75%.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 实木家具成为卖场“新主角”
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

但是政客们究竟会做什么呢?虽然特朗普总统致力于让传统制造业岗位回流美国,但美国好几个州正在试验其他政策来帮助无保障的低收入工人。这些政策各有不同,既有大幅提高最低工资标准的措施,也有阻止雇主在最后一刻调整员工时间表的新规。
她说:”波比就像是小碧昂斯,一个小淑女。”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

怎样画漫画?Manga 就是日本词"漫画"。
第一种是把亚洲视作一个被证明为排斥快速发展的市场,在起飞之前需要重大结构和监管改变。第二种是看到突然出现上行惊喜的可能性。
Traders heading for the exits: 'Unsustainable trends can survive much longer than most people anticipate, but they do end when their 'time is up, at the culmination of their time cycles.' They analyzed more than 20 cycles: 'Nearly unanimously point to tectonic shifts in the months and years ahead.'
媒体非常令人讨厌,我们知道这一点,殿下,但您(以及您所代表的王室)可以用更有尊严的方式来表达您的关切。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

用户在百度搜索平台上最常点阅的新闻事件是,为纪念二战胜利70周年于9月3日在北京举行的阅兵仪式。在此次庆祝活动中,上万名军人接受了现任国家主席习近平、前任主席胡锦涛和江泽民,以及多位外国领导人的检阅,其中包括俄罗斯总统弗拉基米尔·V·普京(Vladimir V. Putin)。
1月份中国居民消费价格指数(CPI)出现上涨,在本月金融市场动荡为主的背景下,该消息对于这个世界第二大经济体来说是个令人鼓舞的迹象。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 房企竞相加入城市更新“主战场”
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Company: Eventbrite
8.触感人造手

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

今年最令人惊喜的消息还包括油价下跌。经济学家对油价下跌的经济影响也是见仁见智,一方面认为消费者因此节省了不少油钱,一方面则认为这种趋势会影响石油的开采钻探活动。但大家普遍认为这会影响小型车和混合动力车的销量。油价下跌加上车价过高,使得凯迪拉克公司的电动轿跑ELR稳居2014年最不受欢迎的车型“宝座”。11月份,这款售价高达8万美元的电动跑车只卖出了155辆。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

《一名拍摄黑手党的西西里摄影师和她的“鲜血档案”》(A Sicilian Photographer of the Mafia and Her ‘Archive of Blood’)
Lori Steele
Even though we are apart, you are in my heart this season.千山万水,隔不断我在佳节对你的思念。
She also said that in the longer-term the other “R” was “reset”, by which she explained that monetary and fiscal policies around the world still had a long way to go before they could be classed as normal. “The final reset is those structural reforms that are necessary in all corners of the world,” she added.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

['regju.leit,'regjuleit]
[r?'m?ntik]

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 新房上保险 业主可索赔
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

剩下的流行语,我们列在这里:
The Amsterdam crisis began when a Dutch group known as the Seppenwolde syndicate made a big, contrarian bet on the shares of East India Company. Those shares had plunged in 1771 mainly because of losses in Bengal, but the company kept paying high dividends and covered up its shortfalls by borrowing money. Convinced that East India shares would quickly rebound, the Seppenwolde group aggressively bought them on margin. But instead of rebounding, the shares fell even further after the company slashed its dividend.
adj. 令人厌烦的

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Most Catholics (60 percent) and white non-evangelical Protestants (65 percent) say they believe disasters like hurricanes and floods are the result of climate change.
It's hard to imagine LOST without Jack Shephard as the group leader. Where would the show have been without him? Had the show's writers gotten their way, we would have learned the answer to that question. When the show was pitched to ABC, Jack Shephard's character was supposed to be killed after the pilot episode, and Kate was supposed to take on more of a leadership role in the series.
Neighborhoods

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

compromise
其中包括“qwerty”(键盘字母顺序,排名第4)、“admin”(管理员,排名第11)和“login”(登录,排名第14)。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Meanwhile, he was being ferried around the globe to tech conferences, getting introduced to other potential investors. D'Aloisio made a remarkable impression on everyone he crossed paths with. 'He has an eerie maturity,' says Andrew Halls, headmaster of the King's College School in Wimbledon, which D'Aloisio has attended since he was 11. 'He has an extraordinary articulateness in the face of situations that, for me, even as a 54-year-old, might be terrifying.'
明星大撞衫 看谁更好看(二)
4. Slacking at school

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

在土耳其问题上,普京表示,他看不到与现任土耳其领导人消除紧张关系的可能性。土耳其不久前击落了一架俄罗斯战机。他说,他非常震惊地看到,土耳其非但没有对其行为做出解释,反而转向北约寻求帮助。
And second, while perceptions haven't changed much, the reality has: Making sure stuff gets where it needs to go, as cheaply and efficiently as possible, has evolved into a high-tech, high-stakes game that calls for a scarce combination of "hard" and "soft" skills.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

The book reflects growing anxiety in some quarters about the possible negative impact of automation on jobs, from manufacturing to professional services. The subtitle of its UK edition warns of “the threat of mass unemployment” and, in the US edition, foresees “a jobless future”.
在经历了性骚扰丑闻频频曝光(从硅谷开始,蔓延至几乎所有行业)的一年后,女性将试图利用这一势头来推动永久性变革。鉴于科技行业的黑人和拉丁裔雇员少之又少,人们将关注被边缘化的少数族裔的困境。
1月份,中国的进口同比减少了14.4%,降至7375亿元人民币。大于去年12月4%的降幅,也和上升1.8%的预期不符。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

9、另一地球

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 韩国水泥业赤字1万亿
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

survey
补救办法:虽然自己当老板的想法很诱人,但并不是每个人都适合创业。创造属于自己的事业,让家人过上幸福生活,改善顾客的生活,这些听起来肯定很浪漫,但漫长的工作时间、没有闲暇时间、承担资金风险,身兼老板、职员、营销人员、会计和门卫等多个职位于一身,这些你能承受吗?如果你喜欢稳定的工作和专注于某项具体任务而不是身兼多职,又或者你不喜欢冒险,你就无法想象整天为工作忙碌的生活。如果你属于以上情况,那么创业并不适合你。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

肺的一项意外功能被发现了。研究人员发现肺不仅仅能促进呼吸作用,在造血方面也起关键作用,肺每小时能制造1000多万血小板(微小的血细胞),这相当于任何特定时刻循环中的血小板的大多数。
苹果(Apple)本周将考验客户的忠诚度、购买力以及对创新的热情,发布第一款售价高达1000美元的iPhone。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Sari Davidson
本周一的谷歌首页涂鸦看起来十分意想天开,但关注却是一个非常严肃的问题:净水。该作品出自一名来自纽约长岛的11岁孩子之手,相当不错。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

The city of 21 million people recorded 1.86 trillion yuan in total consumption in 2015, marking a yearly rise of 8.7 percent. Consumption contributed over 70 percent to the city's GDP growth.
Most entrepreneurs (78 per cent)used savings or relied on friends and family to raise all or part of their start-up funds. Angel financing was also a source for a quarter of entrepreneurs.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 风口上的大家居 是馅饼还是陷阱?
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

该榜单囊括了2015年度全球最具影响力、最智慧性感、人气最高、事业最为成功的美丽女性。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Explaining the choice, the company cited “societal movements toward gender equality and fluidity, the consumer’s increased comfort with using color as a form of expression, a generation that has less concern about being typecast or judged and an open exchange of digital information that has opened our eyes to different approaches to color usage.”
Saving Cancer Patients in Africa
《边桥谜案》(The Bridge),Hulu,周五播出。这部丹麦、瑞典合拍的犯罪剧即将迎来第二季(FX的同名剧集就是根据它改编的,最近刚刚被砍掉),新的一季仍与连接两个乡村的奥莱桑德桥有关。
The Gwen Stefani campaign ran on several apps, including Tango, the Silicon Valley-based messaging app. Tango earns money on ads within a user’s inbox, but it has adopted Swyft’s platform because the ads are in line with the way people already use Tango, says Richard Rabbat, vice president of Advertising and Platform at Tango. A year ago, Tango decided not to sell stickers, because asking users for money creates too much friction, he says. “Putting a payment gate in the way of communication is not the right experience we want to give to our users,” Rabbat says. Ergo, ad campaigns from Swyft.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

"He was not on the intelligence services' radar," added the prime minister.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

另外一件性玩具则显然属于中国皇室。
The requirements come from one of two newly issued regulations over the taxi and online ride-hailing services by China's transportation authority. The regulations will take effect in October and November respectively.
but that was markedly lower than the previous month’s rise of 8.2 per cent.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Note that grosses are not the same thing as earnings. Downey outearned Johnson by $29 million with $75 million in estimated earnings between June 2012 and June 2013, the period we used for the latest edition of our Celebrity 100 list. The numbers we’re looking at here are how many dollars each star’s movies brought in at the box office worldwide this year.
Based on the children's books that goes by the same name, this movie follows the adventures of Mowgli through the Jungle as he tries to discover himself. He comes across several creatures in the Jungle, played by various actors, who make his journey difficult.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

n. 失业,失业人数
最新名单显示香港大学排名第三,澳门大学排名第六。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

研究集团龙洲经讯(Gavekal Dragonomics)的陈龙表示,如今分析师们认为,中国银行业的盈利性增长机会差不多用完了。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

考夫曼和同事加雷思?哈里斯(Gareth Harris)发现,居住在那些人种快速多样化地域的英国白人更倾向于投给右翼的英国国家党(British National Party)。宾夕法尼亚大学政治学教授丹尼尔?霍普金斯(Daniel Hopkins)在美国发现了相似的民族变化导致反移民政策的规律。
Several car names were among the top 50, from ‘ferrari’ to ‘mercedes.’
节目28 歌曲《留声2012》①《滴答》(表演者:侃侃、李晨)②《我的歌声里》(表演者:曲婉婷、杜淳)

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

8.出租车司机
bene好,fit做-做事后的好处
3. 捷蓝航空(JetBlue) 品牌喜爱度:40%/排名:218
优秀老板看起来都会拥有的一个关键是:他们都是解决问题的高手。他们不仅能够发现问题,并能头脑风暴出成功创新的方法来解决问题。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

“我非常激动,皮草被禁止参加伦敦时装周是个巨大的进步!” 费斯回应道。
007电影中,反派人物往往没有自己的主题曲,但是《金枪人》中克里斯多弗·李扮演的暗杀者出场时有一段轻快动人的绝妙曲调,衬托出暗杀者如地狱使者般帅气冷酷。LuLu的演唱完全演绎出这个反派斯卡拉孟加的过人之处。即使这首歌在今天来说欢快得有点可笑,但这也增添了它的魅力。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

你没有赚到足够多的钱来支付日常开销
单词continuous 联想记忆:
She emotes with some of Pink's husky attitude and some of Sia's theatrical so-over-it-ness, but she's a warmer singer than either, whether shrugging off a lover on the self-explanatory "IDGAF" or matching Miguel's intensity on the steamy "Lost in Your Light."

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 助力青年抓住大湾区机遇
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他补充说道:“我很兴奋能有机会重返中国,并享受这个国家的文化以及把NBA现场比赛的激动直接带给中国球迷。”
珍妮弗 洛佩兹

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